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(Aminooxy)acetamide-Val-Cit-PAB-MMAE

Product Sizes
5 mg
£ POA
HY-153263-5MG
10 mg
£ POA
HY-153263-10MG
1 mg
£ POA
HY-153263-1MG
About this Product
SKU:
HY-153263
Application:
Antibody Microarray
CAS Number:
2446645-88-9
Extra Details:
(Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy)acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab; to make ADC[1].
Molecular Weight:
1196.48
Purity:
96.87
References:
[1]Ouberai Myriam, et al. Preparation of antibody-drug conjugates using polymers and crosslinkers. World Intellectual Property Organization, WO2020128488 A1. 2020-06-25.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; sealed storage; away from moisture and light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Pathway:
Antibody-drug Conjugate/ADC Related
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