(±)-AMG 487
Product Sizes
10 mg
£ POA
HY-15319A-10MG
About this Product
- SKU:
- HY-15319A
- Application:
- Antibody Microarray
- CAS Number:
- 947536-03-0
- Extra Details:
- (±)-AMG 487 is a racemate of AMG 487. AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM; respectively[1].
- Molecular Weight:
- 603.59
- References:
- [1]Johnson M, et al. Discovery and optimization of a series of quinazolinone-derived antagonists of CXCR3. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3339-43.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Immunology/Inflammation
