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Molecular Biology

3’-Deoxy-3’-azido-isocytidine

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HY-152737-1EACH
About this Product
SKU:
HY-152737
Application:
Antibody Microarray
CAS Number:
2095417-77-7
Extra Details:
3’-Deoxy-3’-azido-isocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis; induction of apoptosis; etc[1]. 3’-Deoxy-3’-azido-isocytidine is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molecular Weight:
268.23
References:
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Research Area:
Others
Shipping Conditions:
Ambient
Type:
Molecular Biology Reagents: Nucleic Acids
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