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Molecular Biology

3’-Azido-3’-deoxyuridine

Product Sizes
10 mg
£ POA
HY-152720-10MG
1 mg
£ POA
HY-152720-1MG
5 mg
£ POA
HY-152720-5MG
About this Product
SKU:
HY-152720
Application:
Antibody Microarray
CAS Number:
70580-88-0
Extra Details:
3’-Azido-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis; induction of apoptosis; etc[1]. 3’-Azido-3’-deoxyuridine is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molecular Weight:
269.21
Purity:
99.97
References:
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Research Area:
Others; Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Cell Cycle/DNA Damage
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