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Molecular Biology

2′-O-2-Propyn-1-ylguanosine

Product Sizes
5 mg
£ POA
HY-152684-5MG
10 mg
£ POA
HY-152684-10MG
1 mg
£ POA
HY-152684-1MG
About this Product
SKU:
HY-152684
Application:
Antibody Microarray
CAS Number:
206552-86-5
Extra Details:
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models; they also induce type I interferons; producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent; it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
321.29
Purity:
98.46
References:
[1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
Research Area:
Others
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Cell Cycle/DNA Damage
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