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Molecular Biology

5’(R)-C-Methylguanosine

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HY-152652-1EACH
About this Product
SKU:
HY-152652
Application:
Antibody Microarray
CAS Number:
85421-89-2
Extra Details:
5’(R)-C-Methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models; they also induce type I interferons; producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Molecular Weight:
297.27
References:
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.|[2]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Molecular Biology Reagents: Nucleic Acids
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