8-Hydroxymethyl guanosine
Product Sizes
5 mg
£ POA
HY-152430-5MG
1 mg
£ POA
HY-152430-1MG
10 mg
£ POA
HY-152430-10MG
About this Product
- SKU:
- HY-152430
- Application:
- Antibody Microarray
- CAS Number:
- 54898-41-8
- Extra Details:
- 8-Hydroxymethyl guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models; they also induce type I interferons; producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
- Molecular Weight:
- 313.27
- References:
- [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.|[2]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Cell Cycle/DNA Damage
