PSI-6206
Product Sizes
100 mg
£ POA
HY-15236-100MG
10 mg
£ POA
HY-15236-10MG
50 mg
£ POA
HY-15236-50MG
5 mg
£ POA
HY-15236-5MG
500 mg
£ POA
HY-15236-500MG
1 g
£ POA
HY-15236-1G
25 mg
£ POA
HY-15236-25MG
10mM/1mL
£ POA
HY-15236-10MM
About this Product
- SKU:
- HY-15236
- Additional Names:
- RO 2433; GS-331007
- CAS Number:
- 863329-66-2
- Extra Details:
- PSI-6206 (RO 2433) is the deaminated derivative of PSI-6130; which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC90 of >100 μM.
- Molecular Weight:
- 260.22
- Purity:
- 99.97
- References:
- [1]Clark JL, et al. Design, Synthesis, and Antiviral Activity of 2'-Deoxy-2'-fluoro-2'-C-methyl-cytidine, a Potent Inhibitor of Hepatitis C Virus Replication. J Med Chem. 2005 Aug 25;48(17):5504-8.|[2]Ma H, et al. Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.
 J Biol Chem. 2007 Oct 12;282(41):29|[3]Wang P, et al. An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase. J Org Chem. 2009 Sep 4;74(17):6819-24.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection
