3’-Azido-3’-deoxy-2-thiouridine
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HY-152353-1EACH
About this Product
- SKU:
- HY-152353
- Application:
- Antibody Microarray
- CAS Number:
- 2305416-00-4
- Extra Details:
- 3’-Azido-3’-deoxy-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis; induction of apoptosis; etc[1]. 3’-Azido-3’-deoxy-2-thiouridine is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 285.28
- References:
- [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
