PD-1/PD-L1-IN-29
Product Sizes
1 mg
£ POA
HY-152240-1MG
5 mg
£ POA
HY-152240-5MG
10 mg
£ POA
HY-152240-10MG
About this Product
- SKU:
- HY-152240
- Application:
- Antibody Microarray
- CAS Number:
- 2665734-13-2
- Extra Details:
- PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions; induces PD-L1 dimerization and internalization; improves its localization to the endoplasmic reticulum; and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity[1].
- Molecular Weight:
- 460.48
- Purity:
- 99.87
- References:
- [1]Chengliang Sun, et al. Novel Small-Molecule PD-L1 Inhibitor Induces PD-L1 Internalization and Optimizes the Immune Microenvironment. J Med Chem. 2022 Dec 29.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
