Ipatasertib (dihydrochloride)
Product Sizes
50 mg
£ POA
HY-15186A-50MG
10 mg
£ POA
HY-15186A-10MG
5 mg
£ POA
HY-15186A-5MG
100 mg
£ POA
HY-15186A-100MG
1 g
£ POA
HY-15186A-1G
2 mg
£ POA
HY-15186A-2MG
200 mg
£ POA
HY-15186A-200MG
500 mg
£ POA
HY-15186A-500MG
10mM/1mL
£ POA
HY-15186A-10MM
25 mg
£ POA
HY-15186A-25MG
About this Product
- SKU:
- HY-15186A
- Additional Names:
- GDC-0068 (dihydrochloride); RG-7440 (dihydrochloride)
- CAS Number:
- 1396257-94-5
- Extra Details:
- Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5; 18 and 8 nM for Akt1; Akt2 and Akt3; respectively.
- Molecular Weight:
- 530.92
- Purity:
- 99.27
- References:
- [1]Blake JF, et al. Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors. J Med Chem. 2012 Sep 27;55(18):8110-27.|[2]Lin J, et al. Targeting activated Akt with GDC-0068, a novel selective Akt inhibitor that is efficacious in multiple tumor models. Clin Cancer Res. 2013 Apr 1;19(7):1760-72.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- PI3K/Akt/mTOR;Stem Cell/Wnt
