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Proteins and Peptides

(E/Z)-Zotiraciclib (citrate)

Product Sizes
50 mg
£ POA
HY-15166B-50MG
10 mg
£ POA
HY-15166B-10MG
100 mg
£ POA
HY-15166B-100MG
5 mg
£ POA
HY-15166B-5MG
10mM/1mL
£ POA
HY-15166B-10MM
25 mg
£ POA
HY-15166B-25MG
About this Product
SKU:
HY-15166B
Additional Names:
(E/Z)-TG02 (citrate); (E/Z)-SB1317 (citrate)
CAS Number:
1204918-73-9
Extra Details:
(E/Z)-Zotiraciclib citrate is a potent CDK2; JAK2; and FLT3 inhibitor[1].
Molecular Weight:
564.59
Purity:
99.83
References:
[1]William AD, et al. Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer. J Med Chem. 2012;55(1):169-196.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Cell Cycle/DNA Damage;Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
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