(E/Z)-Zotiraciclib
Product Sizes
5 mg
£ POA
HY-15166-5MG
50 mg
£ POA
HY-15166-50MG
100 mg
£ POA
HY-15166-100MG
10 mg
£ POA
HY-15166-10MG
10mM/1mL
£ POA
HY-15166-10MM
25 mg
£ POA
HY-15166-25MG
About this Product
- SKU:
- HY-15166
- Additional Names:
- (E/Z)-TG02; (E/Z)-SB1317
- CAS Number:
- 937270-47-8
- Extra Details:
- (E/Z)-Zotiraciclib ((E/Z)-TG02) is a potent inhibitor of CDK2; JAK2 and FLT3 with IC50s of 13; 73 and 56 nM; respectively. (E/Z)-Zotiraciclib effectively inhibits the proliferation of cancer cells; it can be used for the research of cancer[1][2].
- Molecular Weight:
- 372.46
- Purity:
- 99.96
- References:
- [1]William AD, et al. Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kina|[2]Pasha MK, et al. Preclinical metabolism and pharmacokinetics of SB1317 (TG02), a potent CDK/JAK2/FLT3 inhibitor. Drug Metab Lett. 2012 Mar;6(1):33-42.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
