ALK5-IN-10
Product Sizes
25 mg
£ POA
HY-151233-25MG
1 mg
£ POA
HY-151233-1MG
5 mg
£ POA
HY-151233-5MG
10 mg
£ POA
HY-151233-10MG
50 mg
£ POA
HY-151233-50MG
About this Product
- SKU:
- HY-151233
- CAS Number:
- 1352608-94-6
- Extra Details:
- ALK5-IN-10 (Compound 5d) is a TGF-β type I receptor kinase ALK5 inhibitor; with IC50s of 0.007 and 1.98 μM for ALK5 and p38α; respectively. ALK5-IN-10 can be used for the research of cancer[1].
- Molecular Weight:
- 460.33
- References:
- [1]Jin C H, et al. Discovery of N-((4-([1, 2, 4] Triazolo [1, 5-a] Pyridin-6-Yl)-5-(6-Methylpyridin-2-Yl)-1 H-Imidazol-2-Yl) methyl)-2-Fluoroaniline (EW-7197): a highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent. Journal of medicinal chemistry. 2014, 57(10): 4213-4238.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- TGF-beta/Smad
