FITC-labeled ODN 2088 (sodium)
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HY-150738B-1EACH
About this Product
- SKU:
- HY-150738B
- Extra Details:
- FITC-labeled ODN 2088 (sodium) is a potent TLR3; TLR7 and TLR9 inhibitor. FITC-labeled ODN 2088 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm; emission 520 nm) or flow cytometry.
- References:
- [1]Duramad O, et al. Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation. J Immunol. 2005 May 1;174(9):5193-200.|[2]Römmler F, et al. Guanine modification of inhibitory oligonucleotides potentiates their suppressive function. J Immunol. 2013 Sep 15;191(6):3240-53.|[3]Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells. PLoS One. 2015 Feb 19;10(2):e0116703. |[4]Römmler F, et al. Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells. PLoS One. 2015 Feb 19;10(2):e0116703.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
