S07-2010
Product Sizes
25 mg
£ POA
HY-150644-25MG
5 mg
£ POA
HY-150644-5MG
100 mg
£ POA
HY-150644-100MG
10 mg
£ POA
HY-150644-10MG
50 mg
£ POA
HY-150644-50MG
10mM/1mL
£ POA
HY-150644-10MM
About this Product
- SKU:
- HY-150644
- Application:
- Antibody Microarray
- CAS Number:
- 1223194-71-5
- Extra Details:
- S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor; with IC50 values of 0.19; 0.36; 0.47; and 0.73 μM for AKR1C3; AKR1C4; AKR1C1 and AKR1C2; respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells[1].
- Molecular Weight:
- 371.45
- Purity:
- 98.35
- References:
- [1]Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. 2022.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
