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Molecular Biology

FITC-labeled Drisapersen (sodium)

Product Sizes
1 mg
£ POA
HY-150237-1MG
5 mg
£ POA
HY-150237-5MG
10 mg
£ POA
HY-150237-10MG
About this Product
SKU:
HY-150237
Extra Details:
FITC-labeled Drisapersen (sodium) is Drisapersen labeled with FITC. Drisapersen; a antisense oligonucleotide; induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.
Molecular Weight:
7962.60
Purity:
92.99
References:
[1]Flanigan KM, Voit T, Rosales XQ, et al. Pharmacokinetics and safety of single doses of drisapersen in non-ambulant subjects with Duchenne muscular dystrophy: results of a double-blind randomized clinical trial. Neuromuscul Disord. 2014;24(1):16-24.|[2]Voit T, Topaloglu H, Straub V, et al. Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory, randomised, placebo-controlled phase 2 study. Lancet Neurol. 2014;13(10):987-996.
Research Area:
Others
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; sealed storage; away from moisture)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Cell Cycle/DNA Damage;Cytoskeleton
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