FITC-labeled Tominersen (sodium)
Product Sizes
10 mg
£ POA
HY-150236-10MG
1 mg
£ POA
HY-150236-1MG
5 mg
£ POA
HY-150236-5MG
About this Product
- SKU:
- HY-150236
- Extra Details:
- FITC-labeled Tominersen (sodium) is the Tominersen labeled with FITC. Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen can be used for the research of Huntington’s disease (HD).
- Molecular Weight:
- 7654.00
- Purity:
- 97.65
- References:
- [1]Tabrizi SJ, et, al. Targeting Huntingtin Expression in Patients with Huntington's Disease. N Engl J Med. 2019 Jun 13;380(24):2307-2316.|[2]Kordasiewicz HB, et al. Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. Neuron. 2012 Jun 21;74(6):1031-44.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Neuronal Signaling
