Mirodenafil (dihydrochloride)
Product Sizes
5 mg
£ POA
HY-14930A-5MG
50 mg
£ POA
HY-14930A-50MG
100 mg
£ POA
HY-14930A-100MG
10 mg
£ POA
HY-14930A-10MG
10mM/1mL
£ POA
HY-14930A-10MM
About this Product
- SKU:
- HY-14930A
- Additional Names:
- SK-3530 dihydrochloride
- CAS Number:
- 862189-96-6
- Extra Details:
- Mirodenafil (SK3530) dihydrochloride is an orally active; potent; reversible; and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil dihydrochloride is a glucocorticoid receptor (GR) modulator Mirodenafil dihydrochloride activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil dihydrochloride can be used for the research of erectile dysfunction (ED); Alzheimer’s disease (AD) and systemic sclerosis (SSc)[1][2][3].
- Molecular Weight:
- 604.59
- Purity:
- 99.11
- References:
- [1]Park HJ, et al. Mirodenafil for the treatment of erectile dysfunction: a systematic review of the literature. World J Mens Health. 2014 Apr;32(1):18-27.|[2]Kang BW, et al. Phosphodiesterase 5 inhibitor mirodenafil ameliorates Alzheimer-like pathology and symptoms by multimodal actions. Alzheimers Res Ther. 2022 Jul 8;14(1):92.|[3]Roh JS, et al. Mirodenafil ameliorates skin fibrosis in bleomycin-induced mouse model of systemic sclerosis. Anim Cells Syst (Seoul). 2021 Nov 3;25(6):387-395.
- Research Area:
- Endocrinology; Inflammation/Immunology; Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;Stem Cell/Wnt;Vitamin D Related/Nuclear Receptor
