(Rac)-Bedaquiline
Product Sizes
1 mg
£ POA
HY-14881B-1MG
5 mg
£ POA
HY-14881B-5MG
10 mg
£ POA
HY-14881B-10MG
About this Product
- SKU:
- HY-14881B
- Additional Names:
- (Rac)-TMC207; (Rac)-R207910
- CAS Number:
- 654655-80-8
- Extra Details:
- (Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis[1][2].
- Molecular Weight:
- 555.50
- References:
- [1]Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Jun;55(6):483-487. |[2]Sarathy JP, et al. TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug's Uncoupler Activity. Antimicrob Agents Chemother. 2020 Jan 27;64(2):e01540-19.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection
