(S)-Bleximenib (oxalate)
Product Sizes
10 mg
£ POA
HY-148669B-10MG
50 mg
£ POA
HY-148669B-50MG
5 mg
£ POA
HY-148669B-5MG
25 mg
£ POA
HY-148669B-25MG
100 mg
£ POA
HY-148669B-100MG
10mM/1mL
£ POA
HY-148669B-10MM
About this Product
- SKU:
- HY-148669B
- Additional Names:
- (S)-JNJ-75276617 (oxalate); (S)-Menin-MLL inhibitor 24 (oxalate)
- Application:
- Antibody Microarray
- Extra Details:
- (S)-Bleximenib (oxalate) is a S-Enantiomer of Bleximenib oxalate (HY-148669A). Bleximenib (JNJ-75276617) oxalate is an orally active and selective menin-KMT2A inhibitor; with IC50 values of 0.1 nM; 0.045 nM; and ≤0.066 nM for humans; mice; and dogs; respectively. Bleximenib oxalate can inhibit the proliferation and induce apoptosis and differentiation of tumor cells. Bleximenib oxalate can be used in the research of tumors such as leukemia[1].
- Molecular Weight:
- 689.82
- Purity:
- 98.37
- References:
- [1]DASKALAKIS N, et, al. Combination therapies. WO2022237720A1.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Epigenetics;Protein Tyrosine Kinase/RTK
