Avacincaptad pegol
Product Sizes
10 mg
£ POA
HY-148457-10MG
5 mg
£ POA
HY-148457-5MG
1 mg
£ POA
HY-148457-1MG
About this Product
- SKU:
- HY-148457
- Additional Names:
- Izervay
- CAS Number:
- 1613641-69-2
- Extra Details:
- Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5; and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b; which forms the membrane attack complex (C5b-9); thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA[1][2].
- Molecular Weight:
- 52603 (Approximately)
- Research Area:
- Infection;Inflammation/Immunology;Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
