Elebsiran sodium
Product Sizes
10 mg
£ POA
HY-147266-10MG
5 mg
£ POA
HY-147266-5MG
1 mg
£ POA
HY-147266-1MG
About this Product
- SKU:
- HY-147266
- Additional Names:
- VIR-2218 sodium
- Extra Details:
- Elebsiran (VIR-2218) sodium is a siRNA that targets and degrades hepatitis B virus (HBV) and hepatitis D virus (HDV) RNA transcripts. Elebsiran sodium leads to a significant decrease in HBV surface antigen (HBsAg) and a reduction in viral load. Elebsiran sodium binds to the sialic acid-depleted glycoprotein receptor (ASGPR) on the surface of liver cells through the GalNAc ligand; achieving liver-targeted delivery and demonstrating improved liver safety. Elebsiran sodium can be used for the study of chronic HBV/HDV infections[1][2][3].
- Molecular Weight:
- 14976.67 (free acid)
- Purity:
- 95.83
- References:
- [1]WHO Drug Information. International Nonproprietary Names for Pharmaceutical
- Research Area:
- Infection
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Anti-infection;Epigenetics
