HS-276 (formic)
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HY-147141B-1EACH
About this Product
- SKU:
- HY-147141B
- Extra Details:
- HS-276 formic is an orally active; potent and highly selective TAK1 inhibitor; with a Ki of 2.5 nM. HS-276 formic shows significant inhibition of TAK1; CLK2; GCK; ULK2; MAP4K5; IRAK1; NUAK; CSNK1G2; CAMKKβ-1; and MLK1; with IC50 values of 8.25; 29; 33; 63; 125; 264; 270; 810; 1280; and 5585 nM; respectively. HS-276 formic reduces the expression of TNF; IL-6; and IL-1β. HS-276 formic can be used for rheumatoid arthritis (RA) research[1].
- Molecular Weight:
- 465.54
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
