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Proteins and Peptides

(3S;5R)-Fluvastatin-d6

Product Sizes
1 mg
£ POA
HY-14664DS-1MG
About this Product
SKU:
HY-14664DS
Additional Names:
(3S;5R)-XU 62-320-d6 (free acid)
Application:
Antibody Microarray
CAS Number:
2249799-34-4
Extra Details:
(3S;5R)-Fluvastatin-d6 is the deuterium labeled (3S;5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic; competitive?HMG-CoA reductase?inhibitor with an IC50?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1].
Molecular Weight:
417.50
References:
[1]Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.|[2]Makabe S, Takahashi Y, Watanabe H, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.|[3]Makabe S, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.
Research Area:
Cancer; Cardiovascular Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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