(3R;5S)-Fluvastatin
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HY-14664B-1EACH
About this Product
- SKU:
- HY-14664B
- Additional Names:
- (3R;5S)-XU 62-320 (free acid)
- Application:
- Antibody Microarray
- CAS Number:
- 155229-75-7
- Extra Details:
- (3R;5S)-Fluvastatin is the 3R;5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic; competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
- Molecular Weight:
- 411.47
- References:
- [1]Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.|[2]Makabe S, Takahashi Y, Watanabe H, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.|[3]Makabe S, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.
- Research Area:
- Cancer; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
