PD-1/PD-L1-IN-23
Product Sizes
100 mg
£ POA
HY-145774-100MG
25 mg
£ POA
HY-145774-25MG
10 mg
£ POA
HY-145774-10MG
5 mg
£ POA
HY-145774-5MG
50 mg
£ POA
HY-145774-50MG
10mM/1mL
£ POA
HY-145774-10MM
About this Product
- SKU:
- HY-145774
- Application:
- Antibody Microarray
- CAS Number:
- 2597056-04-5
- Extra Details:
- PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester proagent of L7. L7 is a benzo[c][1;2;5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice[1].
- Molecular Weight:
- 703.41
- Purity:
- 99.98
- References:
- [1]Liu L, et al. Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity. J Med Chem. 2021;64(12):8391-8409.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
