(R/S)-Alicaforsen
Product Sizes
1 mg
£ POA
HY-145728B-1MG
5 mg
£ POA
HY-145728B-5MG
10 mg
£ POA
HY-145728B-10MG
About this Product
- SKU:
- HY-145728B
- Additional Names:
- (R/S)-ISIS-2302
- Extra Details:
- (R/S)-Alicaforsen is the racemate of Alicaforsen composed of R and S configurations. Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production; which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.
- Molecular Weight:
- 6781.27
- Purity:
- 99.27
- References:
- [1]Henry SP, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice. Antisense Nucleic Acid Drug Dev. 1997;7(5):473-481.|[2]Henry SP, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice. Antisense Nucleic Acid Drug Dev. 1997;7(5):473-481.|[3]Henry SP, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a four-week study in cynomolgus monkeys. Toxicology. 1997;120(2):145-155.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Cytoskeleton
