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Molecular Biology

Alicaforsen (sodium)

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HY-145728A-1EACH
About this Product
SKU:
HY-145728A
Additional Names:
ISIS-2302 (sodium)
CAS Number:
331257-52-4
Extra Details:
Alicaforsen (ISIS-2302) sodium is an oligonucleotide and immunostimulant targeting human ICAM-1 mRNA. Alicaforsen sodium hybridizes to specific sites to reduce the expression level of ICAM-1. Alicaforsen sodium is applicable to relevant research on psoriasis; rheumatoid arthritis and inflammatory bowel disease[1].
Molecular Weight:
6370.15 (free acid)
References:
[1]Henry SP, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a four-week study in cynomolgus monkeys. Toxicology. 1997;120(2):145-155.|[2]Henry SP, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice. Antisense Nucleic Acid Drug Dev. 1997;7(5):473-481.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Type:
Molecular Biology Reagents: Nucleic Acids
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