Pelitrexol
Product Sizes
100 mg
£ POA
HY-14530-100MG
50 mg
£ POA
HY-14530-50MG
1 mg
£ POA
HY-14530-1MG
5 mg
£ POA
HY-14530-5MG
10 mg
£ POA
HY-14530-10MG
10mM/1mL
£ POA
HY-14530-10MM
About this Product
- SKU:
- HY-14530
- Additional Names:
- AG 2037
- Application:
- Antibody Microarray
- CAS Number:
- 446022-33-9
- Extra Details:
- Pelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT); a purine biosynthetic enzyme. Pelitrexol also inhibits mTORC1 by reducing GTP-bound Rheb level; a mTORC1 obligate activator. Pelitrexol shows robust tumor growth suppression in mice[1].
- Molecular Weight:
- 463.51
- Purity:
- 98.07
- References:
- [1]Emmanuel N, et al. Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase. Cell Rep. 2017 Jun 27;19(13):2665-2680.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage
