PD-1/PD-L1-IN-13
Product Sizes
100 mg
£ POA
HY-145239-100MG
5 mg
£ POA
HY-145239-5MG
25 mg
£ POA
HY-145239-25MG
10 mg
£ POA
HY-145239-10MG
50 mg
£ POA
HY-145239-50MG
10mM/1mL
£ POA
HY-145239-10MM
About this Product
- SKU:
- HY-145239
- Application:
- Antibody Microarray
- CAS Number:
- 2865841-81-0
- Extra Details:
- PD-1/PD-L1-IN-13 (Compound 43) is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM. PD-1/PD-L1-IN-13 promots CD8+ T cell activation and delays the tumor growth in the Hepa1-6 syngeneic mouse model[1].
- Molecular Weight:
- 726.12
- Purity:
- 99.52
- References:
- [1]Song Z, et al. Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage. J Med Chem. 2021;64(22):16687-16702.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
