BSJ-01-175
Product Sizes
10 mg
£ POA
HY-145072-10MG
5 mg
£ POA
HY-145072-5MG
25 mg
£ POA
HY-145072-25MG
50 mg
£ POA
HY-145072-50MG
100 mg
£ POA
HY-145072-100MG
About this Product
- SKU:
- HY-145072
- CAS Number:
- 2227392-55-2
- Extra Details:
- BSJ-01-175 is a potent and selective CDK12/13 covalent inhibitor. BSJ-01-175 demonstrates exquisite selectivity; potent inhibition of RNA polymerase II phosphorylation; and downregulation of CDK12-targeted genes in cancer cells[1].
- Molecular Weight:
- 545.08
- Purity:
- 99.88
- References:
- [1]Jiang B, et al. Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma. Eur J Med Chem. 2021;221:113481.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage
