ML 10302 (hydrochloride)
Product Sizes
50 mg
£ POA
HY-14442-50MG
25 mg
£ POA
HY-14442-25MG
10 mg
£ POA
HY-14442-10MG
100 mg
£ POA
HY-14442-100MG
5 mg
£ POA
HY-14442-5MG
About this Product
- SKU:
- HY-14442
- Application:
- Electron Microscopy
- CAS Number:
- 186826-17-5
- Extra Details:
- ML 10302 hydrochloride is a potent and selective 5-HT4 receptor agonist; with an EC50 of 4 nM. ML 10302 hydrochloride displays more than 680-fold selectivity over 5-HT3 receptor in binding assay[1][2].
- Molecular Weight:
- 349.25
- References:
- [1]Langlois, M., et al. Design of a potent 5-HT4 receptor agonist with nanomolar affinity. Bioorganic & Medicinal Chemistry Letters. 1994. 4(12), 1433–1436.|[2]D Yang, et al. New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. J Med Chem. 1997 Feb 14;40(4):608-21.|[3]M Cachard-Chastel, et al. 5-HT4 receptor agonists increase sAPPα levels in the cortex and hippocampus of male C57BL/6j mice. Br J Pharmacol. 2007 Apr; 150(7): 883–892.
- Research Area:
- Metabolic Disease; Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Neuronal Signaling
