PD-1/PD-L1-IN-14
Product Sizes
25 mg
HY-144258-25MG
10 mg
HY-144258-10MG
100 mg
HY-144258-100MG
50 mg
HY-144258-50MG
5 mg
HY-144258-5MG
10mM/1mL
HY-144258-10MM
About this Product
- SKU:
- HY-144258
- CAS Number:
- 2499965-12-5
- Extra Details:
- PD-1/PD-L1-IN-14 (compound 17) is a bifunctional inhibitor of PD-1/PD-L1 interactions; with an IC50 of 27.8 nM. PD-1/PD-L1-IN-14 (compound 17) inhibits PD-1/PD-L1 interactions and promotes dimerization; internalization; and degradation of PD-L1[1].
- Molecular Weight:
- 400.47
- Purity:
- 99.60
- References:
- [1]Tianyu Wang, et al. Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation. J Med Chem. 2022 Mar 10;65(5):3879-3893.
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
