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Proteins and Peptides

(Rac)-PF-998425

Product Sizes
5 mg
£ POA
HY-14250A-5MG
50 mg
£ POA
HY-14250A-50MG
10 mg
£ POA
HY-14250A-10MG
100 mg
£ POA
HY-14250A-100MG
10mM/1mL
£ POA
HY-14250A-10MM
25 mg
£ POA
HY-14250A-25MG
About this Product
SKU:
HY-14250A
Application:
Electron Microscopy
CAS Number:
1076225-26-7
Extra Details:
(Rac)-PF-998425 is a potent; selective; nonsteroidal androgen receptor (AR) antagonist. (Rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays; respectively. (Rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
Molecular Weight:
269.26
Purity:
99.68
References:
[1]Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.
Research Area:
Endocrinology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Vitamin D Related/Nuclear Receptor
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