2';3'-cGAMP-C2-PPA
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HY-141662-1EACH
About this Product
- SKU:
- HY-141662
- Application:
- Antibody Microarray
- CAS Number:
- 2586047-11-0
- Extra Details:
- 2’;3’-cGAMP-C2-PPA is a cyclic dinucleotide interferon gene-stimulating protein (STING) agonist. 2’;3’-cGAMP-C2-PPA is a drug conjugated conjugate used to target antibody-drug conjugated conjugate (ADC) for the treatment of cancer. 2’;3’-cGAMP-C2-PPA can be used in the study of immune and tumor-related diseases[1][2][3].
- Molecular Weight:
- 850.71
- References:
- [1]Chen Z, et, al. Antibody-sting agonist conjugates and their use in immunotherapy. US20210015941A1.|[2]Stazzoni S, et al. Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists. Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202207175.|[3]Zhang X, et al GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol Cell. 2013 Jul 25;51(2):226-35
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
