(S)-Veliflapon
Product Sizes
50 mg
£ POA
HY-14165A-50MG
5 mg
£ POA
HY-14165A-5MG
10 mg
£ POA
HY-14165A-10MG
25 mg
£ POA
HY-14165A-25MG
100 mg
£ POA
HY-14165A-100MG
10mM/1mL
£ POA
HY-14165A-10MM
About this Product
- SKU:
- HY-14165A
- Additional Names:
- (S)-BAY X 1005; (S)-DG-031
- CAS Number:
- 128253-32-7
- Extra Details:
- (S)-Veliflapon ((S)-BAY X 1005) is an orally active inhibitor of leukotriene biosynthesis and 5-lipoxygenase activating protein (FLAP). (S)-Veliflapon inhibits the formation of leukotriene B4 (LTB4) in rat; mouse and human leukocytes with IC50 values of 0.026 µM; 0.039 µM and 0.22 µM respectively. (S)-Veliflapon showes enantioselectivity in human whole blood[1][2][3].
- Molecular Weight:
- 361.43
- Purity:
- 99.44
- References:
- [1]Fruchtmann R, et al. In vitro pharmacology of BAY X1005, a new inhibitor of leukotriene synthesis. Agents Actions. 1993 Mar;38(3-4):188-95. |[2]Hermann, David J., et al. Dosing schedules of leukotriene synthesis inhibitors for human therapy. World Intellectual Property Organization. WO2009002746.|[3]Helgadottir, et al. Polymorphisms in the susceptibility genes for myocardial infarction, stroke, and peripheral artery occlusive disease and their use in risk assessment and prophylaxis therapy. United States. US20070280917.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Immunology/Inflammation
