Pinatuzumab vedotin
Product Sizes
1 mg
£ POA
HY-141602-1MG
10 mg
£ POA
HY-141602-10MG
5 mg
£ POA
HY-141602-5MG
About this Product
- SKU:
- HY-141602
- Additional Names:
- anti-CD22-vc-MMAE; DCDT2980S
- Application:
- Antibody Microarray
- CAS Number:
- 1313706-14-7
- Extra Details:
- Pinatuzumab vedotin; an antibody-drug conjugate (ADC); is a CD22 humanized monoclonal antibody Pinatuzumab (HY-P99230) conjugated to VcMMAE (HY-15575). Pinatuzumab vedotin has antitumor activities[1].
- Molecular Weight:
- N/A
- Purity:
- 98.25
- References:
- [1]Ranjana H Advani, et al. Phase I Study of the Anti-CD22 Antibody–Drug Conjugate Pinatuzumab Vedotin with/without Rituximab in Patients with Relapsed/Refractory B-cell Non-Hodgkin Lymphoma. Clinical Trial Clin Cancer Res. 2017 Mar 1;23(5):1167-1176.|[2]Yip, V., et al., (2024). Monomethyl auristatin E (MMAE), a payload for multiple antibody drug conjugates (ADCs), demonstrates differential red blood cell partitioning across human and animal species. Xenobiotica; the fate of foreign compounds in biological systems, 54(8), 511–520.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -80[o]C; protect from light
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton;Immunology/Inflammation
