11β-HSD1-IN-15
Product Sizes
5 mg
£ POA
HY-14156-5MG
10 mg
£ POA
HY-14156-10MG
1 mg
£ POA
HY-14156-1MG
About this Product
- SKU:
- HY-14156
- Application:
- Electron Microscopy
- CAS Number:
- 946398-78-3
- Extra Details:
- 11β-HSD1-IN-15 is an inhibitor of 11β-hydroxysteroid dehydrogenase type I (11β-HSD1). 11β-HSD1-IN-15 blocks the conversion of corticosterone to cortisol by binding to the active site of the 11β-HSD1 enzyme. 11β-HSD1-IN-15 can be used to investigate the role of 11β-HSD1 enzymes IN the development of metabolic syndrome; obesity; cognitive decline and type 2 diabetes[1].
- Molecular Weight:
- 479.88
- References:
- [1]Wan Z K, et al. Efficacious 11β-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model[J]. Journal of medicinal chemistry, 2009, 52(17): 5449-5461.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
