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Proteins and Peptides

Enprofylline

Product Sizes
5 mg
£ POA
HY-14117-5MG
10 mg
£ POA
HY-14117-10MG
About this Product
SKU:
HY-14117
CAS Number:
41078-02-8
Extra Details:
Enprofylline acts as a selective and competitive A2B receptor antagonist with the Ki of 7 μM. Enprofylline also acts as a phosphodiesterase inhibitor. Enprofylline can be used for the research of asthma; chronic obstructive pulmonary disease[1][2][3].
Molecular Weight:
194.19
Purity:
98.71
References:
[1]I Feoktistov, et al. Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest. 1995 Oct;96(4):1979-86.|[2]M B Grant, et al. Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation. Invest Ophthalmol Vis Sci. 2001 Aug;42(9):2068-73.|[3]Jiang-Ning Yang, et al. Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine. Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1141-9.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; protect from light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Metabolic Enzyme/Protease
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