GSK189254A (Standard)
Product Sizes
25 mg
£ POA
HY-14111R-25MG
5 mg
£ POA
HY-14111R-5MG
10 mg
£ POA
HY-14111R-10MG
50 mg
£ POA
HY-14111R-50MG
100 mg
£ POA
HY-14111R-100MG
1 mg
£ POA
HY-14111R-1MG
About this Product
- SKU:
- HY-14111R
- CAS Number:
- 720690-73-3
- Extra Details:
- GSK189254A (Standard) is the analytical standard of GSK189254A. This product is intended for research and analytical applications. GSK189254A (GSK189254 free base) is a novel; potent and selective histamine H3 receptor antagonist with pKi values of 9.59-9.90 and 8.51-9.17 for human and rat H3; respectively.
- Molecular Weight:
- 351.44
- References:
- [1]Medhurst AD, et al. GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models. J Pharmacol Exp Ther. 2007 Jun;321(3):1032-45.|[2]Guo RX, et al. Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice.Br J Pharmacol. 2009 May;157(1):104-17.
- Research Area:
- Neurological Disease; Endocrinology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
