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Azido-PEG8-acid

Product Sizes
100 mg
£ POA
HY-140454-100MG
250 mg
£ POA
HY-140454-250MG
1 g
£ POA
HY-140454-1G
5 g
£ POA
HY-140454-5G
About this Product
SKU:
HY-140454
Application:
Antibody Microarray
CAS Number:
1214319-92-2
Extra Details:
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG8-acid is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molecular Weight:
467.51
Purity:
99.69
References:
[1] Tan M, et al. Peptide-targeted Nanoglobular Gd-DOTA monoamide conjugates for magnetic resonance cancer molecular imaging. Biomacromolecules. 2010 Mar 8;11(3):754-61.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Pathway:
Antibody-drug Conjugate/ADC Related;PROTAC
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