Azido-PEG6-amine
Product Sizes
500 mg
£ POA
HY-140215-500MG
100 mg
£ POA
HY-140215-100MG
50 mg
£ POA
HY-140215-50MG
250 mg
£ POA
HY-140215-250MG
10 g
£ POA
HY-140215-10G
5 g
£ POA
HY-140215-5G
1 g
£ POA
HY-140215-1G
About this Product
- SKU:
- HY-140215
- Application:
- Antibody Microarray
- CAS Number:
- 957486-82-7
- Extra Details:
- Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG6-amine is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 350.41
- Purity:
- 99.86
- References:
- [1]Williams EGL, et al. Glycosylated Reversible Addition-Fragmentation Chain Transfer Polymers with Varying Polyethylene Glycol Linkers Produce Different Short Interfering RNA Uptake, Gene Silencing, and Toxicity Profiles. Biomacromolecules. 2017 Dec 11;18(12):4099-4112.|[2]Philip Wilson Howard, et al. Pyrrolobenzodiazepines and conjugates thereof. WO2014140862A2.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
