Azido-PEG2-C2-amine
Product Sizes
100 mg
£ POA
HY-140213-100MG
250 mg
£ POA
HY-140213-250MG
500 mg
£ POA
HY-140213-500MG
5 g
£ POA
HY-140213-5G
1 g
£ POA
HY-140213-1G
About this Product
- SKU:
- HY-140213
- Additional Names:
- N3-PEG2-CH2CH2NH2
- Application:
- Antibody Microarray
- CAS Number:
- 166388-57-4
- Extra Details:
- Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG2-C2-amine is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 174.20
- Purity:
- 99.85
- References:
- [1]Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 22;62(16):7575-7582.|[2]Tominari, Yusuk , et al. Heterocyclic compound. WO2020027225A1.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
