Azido-PEG3-Val-Cit-PAB-PNP
Product Sizes
10 mg
£ POA
HY-140150-10MG
5 mg
£ POA
HY-140150-5MG
100 mg
£ POA
HY-140150-100MG
25 mg
£ POA
HY-140150-25MG
50 mg
£ POA
HY-140150-50MG
About this Product
- SKU:
- HY-140150
- Application:
- Antibody Microarray
- CAS Number:
- 2055047-18-0
- Extra Details:
- Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG3-Val-Cit-PAB-PNP is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 773.79
- Purity:
- 99.21
- References:
- [1]Dan N, et al. Antibody-Drug Conjugates for Cancer Therapy: Chemistry to Clinical Implications. Pharmaceuticals (Basel). 2018 Apr 9;11(2). pii: E32.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
