Azide-PEG3-Tos
Product Sizes
100 mg
£ POA
HY-140004-100MG
250 mg
£ POA
HY-140004-250MG
10 g
£ POA
HY-140004-10G
5 g
£ POA
HY-140004-5G
1 g
£ POA
HY-140004-1G
About this Product
- SKU:
- HY-140004
- Application:
- Antibody Microarray
- CAS Number:
- 178685-33-1
- Extra Details:
- Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azide-PEG3-Tos is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 329.38
- Purity:
- 99.91
- References:
- [1]Borchmann DE, et al. GRGDS-Functionalized Poly(lactide)-graft-poly(ethylene glycol) Copolymers: Combining Thiol-Ene Chemistry with Staudinger Ligation. Macromolecules. 2013 Jun 11;46(11):4426-4431.|[2]Park, Tae Kyo, et al. Compound bearing beta-galactoside-introduced self-immolative linker. WO2018124758A2.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
