PD-L1-IN-1
Product Sizes
50 mg
£ POA
HY-139781-50MG
100 mg
£ POA
HY-139781-100MG
25 mg
£ POA
HY-139781-25MG
10 mg
£ POA
HY-139781-10MG
5 mg
£ POA
HY-139781-5MG
10mM/1mL
£ POA
HY-139781-10MM
About this Product
- SKU:
- HY-139781
- Application:
- Antibody Microarray
- CAS Number:
- 2767424-13-3
- Extra Details:
- PD-L1-IN-1 (Compound 10) is a potent PD-L1 inhibitor with an IC50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells and peripheral blood mononuclear cells enhanced antitumor immune activity of the latter. PD-L1-IN-1 significantly exhibits low cytotoxicity in healthy cells[1].
- Molecular Weight:
- 377.44
- Purity:
- 98.01
- References:
- [1]Russomanno P, et al. Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors. J Med Chem. 2021;64(21):16020-16045.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
