(S)-GSK-3685032
Product Sizes
100 mg
£ POA
HY-139664B-100MG
10 mg
£ POA
HY-139664B-10MG
50 mg
£ POA
HY-139664B-50MG
5 mg
£ POA
HY-139664B-5MG
25 mg
£ POA
HY-139664B-25MG
10mM/1mL
£ POA
HY-139664B-10MM
About this Product
- SKU:
- HY-139664B
- Application:
- Antibody Microarray
- CAS Number:
- 2170142-58-0
- Extra Details:
- (S)-GSK-3685032 is the isomer of GSK-3685032 (HY-139664); and can be used as an experimental control. GSK-3685032 is a non-time-dependent; noncovalently; first-in-class reversible DNMT1-selective inhibitor; with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation; transcriptional activation; and cancer cell growth inhibition[1].
- Molecular Weight:
- 420.53
- Purity:
- 98.82
- References:
- [1]Pappalardi MB, et al. Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer. 2021;2(10):1002-1017.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Epigenetics
