(+)-JNJ-A07
Product Sizes
10 mg
£ POA
HY-139602-10MG
5 mg
£ POA
HY-139602-5MG
25 mg
£ POA
HY-139602-25MG
10mM/1mL
£ POA
HY-139602-10MM
About this Product
- SKU:
- HY-139602
- CAS Number:
- 2135640-93-4
- Extra Details:
- (+)-JNJ-A07 is a highly potent; orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models[1].
- Molecular Weight:
- 578.96
- Purity:
- 98.46
- References:
- [1]Kaptein SJF, et al. A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction [published correction appears in Nature. 2021 Nov;599(7883):E2]. Nature. 2021;598(7881):504-509.
- Research Area:
- Infection
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection
