(R)-Zunsemetinib
Product Sizes
10 mg
£ POA
HY-139553A-10MG
5 mg
£ POA
HY-139553A-5MG
1 mg
£ POA
HY-139553A-1MG
50 mg
£ POA
HY-139553A-50MG
25 mg
£ POA
HY-139553A-25MG
10mM/1mL
£ POA
HY-139553A-10MM
About this Product
- SKU:
- HY-139553A
- Additional Names:
- (R)-ATI-450; (R)-CDD-450
- CAS Number:
- 1640282-44-5
- Extra Details:
- (R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553); and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases[1].
- Molecular Weight:
- 513.92
- Purity:
- 97.84
- References:
- [1]Zunsemetinib (ATI-450) – Investigational oral MK2 pathway inhibitor|[2]Aclaris Therapeutics Announces ATI-450 (MK2 pathway Inhibitor) publication in Journal of Experimental Medicine|[3]Wang C, et al. Selective inhibition of the p38α MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signals. J Exp Med. 2018;215(5):1315-1325.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Others
